Review



l name srt2104 group  (MedChemExpress)


Bioz Verified Symbol MedChemExpress is a verified supplier
Bioz Manufacturer Symbol MedChemExpress manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 94
      Buy from Supplier

    Structured Review

    MedChemExpress l name srt2104 group
    SIRT1 alleviates PE-like symptoms in the mouse model (A) Schematic illustration of the experimental design. (B) Representative images of the fetuses of the Control, L-NAME, and L-NAME + <t>SRT2104</t> groups; Scale bars:1 cm. (C) Systolic blood pressure of pregnant mice in control (n = 6 dam), L-NAME (n = 7 dams), and L-NAME + SRT2104 group (n = 7 dams). (D–F) Fetal weight, (E) crown-rump length,and (F) placental weight at E18.5 in different groups; n = 85 fetuses from 6 dams in the control group, n = 98 fetuses from 7 dams in the L-NAME group, and n = 81 fetuses from 7 dams in the L-NAME + SRT2104 group. (G) H&E staining of placental sections at E18.5. The LZ and JZ areas and the Lz/Jz ratio were quantified; Scale bars: 1000 μm (upper panel), 200um (lower panel); n = 3. (H) H&E staining of maternal kidney sections at E18.5, and measurement of Bowman space; Scale bars: 200 μm; n = 3. LZ, Labyrinth zone; JZ, Junction zone. One-way ANOVA and Tukey’s multiple comparison test. All data are presented as the means ± SEM.
    L Name Srt2104 Group, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 28 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/srt2104+srt/SRT+2104/pmc13272158-54-3-16
    Average 94 stars, based on 28 article reviews
    l name srt2104 group - by Bioz Stars, 2026-10
    94/100 stars

    Images

    1) Product Images from "The SIRT1–p53 axis drives a ferro-aging-like program and aggravates trophoblast dysfunction in preeclampsia"

    Article Title: The SIRT1–p53 axis drives a ferro-aging-like program and aggravates trophoblast dysfunction in preeclampsia

    Journal: Frontiers in Aging

    doi: 10.3389/fragi.2026.1838730

    SIRT1 alleviates PE-like symptoms in the mouse model (A) Schematic illustration of the experimental design. (B) Representative images of the fetuses of the Control, L-NAME, and L-NAME + SRT2104 groups; Scale bars:1 cm. (C) Systolic blood pressure of pregnant mice in control (n = 6 dam), L-NAME (n = 7 dams), and L-NAME + SRT2104 group (n = 7 dams). (D–F) Fetal weight, (E) crown-rump length,and (F) placental weight at E18.5 in different groups; n = 85 fetuses from 6 dams in the control group, n = 98 fetuses from 7 dams in the L-NAME group, and n = 81 fetuses from 7 dams in the L-NAME + SRT2104 group. (G) H&E staining of placental sections at E18.5. The LZ and JZ areas and the Lz/Jz ratio were quantified; Scale bars: 1000 μm (upper panel), 200um (lower panel); n = 3. (H) H&E staining of maternal kidney sections at E18.5, and measurement of Bowman space; Scale bars: 200 μm; n = 3. LZ, Labyrinth zone; JZ, Junction zone. One-way ANOVA and Tukey’s multiple comparison test. All data are presented as the means ± SEM.
    Figure Legend Snippet: SIRT1 alleviates PE-like symptoms in the mouse model (A) Schematic illustration of the experimental design. (B) Representative images of the fetuses of the Control, L-NAME, and L-NAME + SRT2104 groups; Scale bars:1 cm. (C) Systolic blood pressure of pregnant mice in control (n = 6 dam), L-NAME (n = 7 dams), and L-NAME + SRT2104 group (n = 7 dams). (D–F) Fetal weight, (E) crown-rump length,and (F) placental weight at E18.5 in different groups; n = 85 fetuses from 6 dams in the control group, n = 98 fetuses from 7 dams in the L-NAME group, and n = 81 fetuses from 7 dams in the L-NAME + SRT2104 group. (G) H&E staining of placental sections at E18.5. The LZ and JZ areas and the Lz/Jz ratio were quantified; Scale bars: 1000 μm (upper panel), 200um (lower panel); n = 3. (H) H&E staining of maternal kidney sections at E18.5, and measurement of Bowman space; Scale bars: 200 μm; n = 3. LZ, Labyrinth zone; JZ, Junction zone. One-way ANOVA and Tukey’s multiple comparison test. All data are presented as the means ± SEM.

    Techniques Used: Control, Staining, Comparison

    Related Articles

    Immunoprecipitation:

    Article Title: The Sirt1-Piezo1 Axis Promotes Bone Formation and Repair in Mice.
    Article Snippet: Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).

    Article Title: The Sirt1‐Piezo1 Axis Promotes Bone Formation and Repair in Mice
    Article Snippet: Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).

    Western Blot:

    Article Title: The Sirt1-Piezo1 Axis Promotes Bone Formation and Repair in Mice.
    Article Snippet: Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).

    Article Title: The Sirt1‐Piezo1 Axis Promotes Bone Formation and Repair in Mice
    Article Snippet: Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).

    Transfection:

    Article Title: The Sirt1-Piezo1 Axis Promotes Bone Formation and Repair in Mice.
    Article Snippet: Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).

    Article Title: The Sirt1‐Piezo1 Axis Promotes Bone Formation and Repair in Mice
    Article Snippet: Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).

    Plasmid Preparation:

    Article Title: The Sirt1-Piezo1 Axis Promotes Bone Formation and Repair in Mice.
    Article Snippet: Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).

    Article Title: The Sirt1‐Piezo1 Axis Promotes Bone Formation and Repair in Mice
    Article Snippet: Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).

    Expressing:

    Article Title: The Sirt1-Piezo1 Axis Promotes Bone Formation and Repair in Mice.
    Article Snippet: Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).

    Article Title: The Sirt1‐Piezo1 Axis Promotes Bone Formation and Repair in Mice
    Article Snippet: Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).

    Imaging:

    Article Title: The Sirt1-Piezo1 Axis Promotes Bone Formation and Repair in Mice.
    Article Snippet: Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).

    Article Title: The Sirt1‐Piezo1 Axis Promotes Bone Formation and Repair in Mice
    Article Snippet: Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).

    Mutagenesis:

    Article Title: The Sirt1-Piezo1 Axis Promotes Bone Formation and Repair in Mice.
    Article Snippet: Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).

    Article Title: The Sirt1‐Piezo1 Axis Promotes Bone Formation and Repair in Mice
    Article Snippet: Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).

    Concentration Assay:

    Article Title: The Sirt1-Piezo1 Axis Promotes Bone Formation and Repair in Mice.
    Article Snippet: Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).

    Article Title: The Sirt1‐Piezo1 Axis Promotes Bone Formation and Repair in Mice
    Article Snippet: Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).

    Staining:

    Article Title: The Sirt1-Piezo1 Axis Promotes Bone Formation and Repair in Mice.
    Article Snippet: Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).

    Article Title: The Sirt1‐Piezo1 Axis Promotes Bone Formation and Repair in Mice
    Article Snippet: Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).

    Immunohistochemistry:

    Article Title: The Sirt1-Piezo1 Axis Promotes Bone Formation and Repair in Mice.
    Article Snippet: Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).

    Article Title: The Sirt1‐Piezo1 Axis Promotes Bone Formation and Repair in Mice
    Article Snippet: Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).

    Standard Deviation:

    Article Title: The Sirt1-Piezo1 Axis Promotes Bone Formation and Repair in Mice.
    Article Snippet: Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Preparation of Yeast Microcapsules (YCs) and Cationic Nanoparticles (NPs): Baker’s yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).

    Article Title: The Sirt1‐Piezo1 Axis Promotes Bone Formation and Repair in Mice
    Article Snippet: Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).Baker's yeast (S. cerevisiae) was provided by Leadfree Management Co. Ltd. (Shanghai, China).. Resveratrol (RSV) and SRT2104 (SRT) were obtained from the MedChemExpress (MCE).. The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).The commercial Cy5‐NHS ester and branched polyethyleneimine (bPEI, molecular (weight = 25 kDa) were purchased from Sigma–Aldrich (Missouri, USA).



    Similar Products

    l name srt2104 group  (MedChemExpress)
    94
    MedChemExpress l name srt2104 group
    SIRT1 alleviates PE-like symptoms in the mouse model (A) Schematic illustration of the experimental design. (B) Representative images of the fetuses of the Control, L-NAME, and L-NAME + <t>SRT2104</t> groups; Scale bars:1 cm. (C) Systolic blood pressure of pregnant mice in control (n = 6 dam), L-NAME (n = 7 dams), and L-NAME + SRT2104 group (n = 7 dams). (D–F) Fetal weight, (E) crown-rump length,and (F) placental weight at E18.5 in different groups; n = 85 fetuses from 6 dams in the control group, n = 98 fetuses from 7 dams in the L-NAME group, and n = 81 fetuses from 7 dams in the L-NAME + SRT2104 group. (G) H&E staining of placental sections at E18.5. The LZ and JZ areas and the Lz/Jz ratio were quantified; Scale bars: 1000 μm (upper panel), 200um (lower panel); n = 3. (H) H&E staining of maternal kidney sections at E18.5, and measurement of Bowman space; Scale bars: 200 μm; n = 3. LZ, Labyrinth zone; JZ, Junction zone. One-way ANOVA and Tukey’s multiple comparison test. All data are presented as the means ± SEM.
    L Name Srt2104 Group, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/srt2104+srt/SRT+2104/pmc13272158-54-3-16
    Average 94 stars, based on 1 article reviews
    l name srt2104 group - by Bioz Stars, 2026-10
    94/100 stars
    		  Buy from Supplier
    srt2104  (TargetMol)
    92
    TargetMol srt2104
    SIRT1 alleviates PE-like symptoms in the mouse model (A) Schematic illustration of the experimental design. (B) Representative images of the fetuses of the Control, L-NAME, and L-NAME + <t>SRT2104</t> groups; Scale bars:1 cm. (C) Systolic blood pressure of pregnant mice in control (n = 6 dam), L-NAME (n = 7 dams), and L-NAME + SRT2104 group (n = 7 dams). (D–F) Fetal weight, (E) crown-rump length,and (F) placental weight at E18.5 in different groups; n = 85 fetuses from 6 dams in the control group, n = 98 fetuses from 7 dams in the L-NAME group, and n = 81 fetuses from 7 dams in the L-NAME + SRT2104 group. (G) H&E staining of placental sections at E18.5. The LZ and JZ areas and the Lz/Jz ratio were quantified; Scale bars: 1000 μm (upper panel), 200um (lower panel); n = 3. (H) H&E staining of maternal kidney sections at E18.5, and measurement of Bowman space; Scale bars: 200 μm; n = 3. LZ, Labyrinth zone; JZ, Junction zone. One-way ANOVA and Tukey’s multiple comparison test. All data are presented as the means ± SEM.
    Srt2104, supplied by TargetMol, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/srt2104+srt/SRT+2104/pm40889626-35-0-6
    Average 92 stars, based on 1 article reviews
    srt2104 - by Bioz Stars, 2026-10
    92/100 stars
    		  Buy from Supplier
    sirtuin 1 activator srt2104  (MedChemExpress)
    94
    MedChemExpress sirtuin 1 activator srt2104
    SIRT1 alleviates PE-like symptoms in the mouse model (A) Schematic illustration of the experimental design. (B) Representative images of the fetuses of the Control, L-NAME, and L-NAME + <t>SRT2104</t> groups; Scale bars:1 cm. (C) Systolic blood pressure of pregnant mice in control (n = 6 dam), L-NAME (n = 7 dams), and L-NAME + SRT2104 group (n = 7 dams). (D–F) Fetal weight, (E) crown-rump length,and (F) placental weight at E18.5 in different groups; n = 85 fetuses from 6 dams in the control group, n = 98 fetuses from 7 dams in the L-NAME group, and n = 81 fetuses from 7 dams in the L-NAME + SRT2104 group. (G) H&E staining of placental sections at E18.5. The LZ and JZ areas and the Lz/Jz ratio were quantified; Scale bars: 1000 μm (upper panel), 200um (lower panel); n = 3. (H) H&E staining of maternal kidney sections at E18.5, and measurement of Bowman space; Scale bars: 200 μm; n = 3. LZ, Labyrinth zone; JZ, Junction zone. One-way ANOVA and Tukey’s multiple comparison test. All data are presented as the means ± SEM.
    Sirtuin 1 Activator Srt2104, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/srt2104+srt/SRT+2104/10__1016_slash_j__foodres__2026__118395-126-36-40
    Average 94 stars, based on 1 article reviews
    sirtuin 1 activator srt2104 - by Bioz Stars, 2026-10
    94/100 stars
    		  Buy from Supplier
    srt2104  (MedChemExpress)
    94
    MedChemExpress srt2104
    SIRT1 alleviates PE-like symptoms in the mouse model (A) Schematic illustration of the experimental design. (B) Representative images of the fetuses of the Control, L-NAME, and L-NAME + <t>SRT2104</t> groups; Scale bars:1 cm. (C) Systolic blood pressure of pregnant mice in control (n = 6 dam), L-NAME (n = 7 dams), and L-NAME + SRT2104 group (n = 7 dams). (D–F) Fetal weight, (E) crown-rump length,and (F) placental weight at E18.5 in different groups; n = 85 fetuses from 6 dams in the control group, n = 98 fetuses from 7 dams in the L-NAME group, and n = 81 fetuses from 7 dams in the L-NAME + SRT2104 group. (G) H&E staining of placental sections at E18.5. The LZ and JZ areas and the Lz/Jz ratio were quantified; Scale bars: 1000 μm (upper panel), 200um (lower panel); n = 3. (H) H&E staining of maternal kidney sections at E18.5, and measurement of Bowman space; Scale bars: 200 μm; n = 3. LZ, Labyrinth zone; JZ, Junction zone. One-way ANOVA and Tukey’s multiple comparison test. All data are presented as the means ± SEM.
    Srt2104, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/srt2104+srt/SRT+2104/pm41531169-41-14-63
    Average 94 stars, based on 1 article reviews
    srt2104 - by Bioz Stars, 2026-10
    94/100 stars
    		  Buy from Supplier
    srt2104 srt  (MedChemExpress)
    94
    MedChemExpress srt2104 srt
    SIRT1 alleviates PE-like symptoms in the mouse model (A) Schematic illustration of the experimental design. (B) Representative images of the fetuses of the Control, L-NAME, and L-NAME + <t>SRT2104</t> groups; Scale bars:1 cm. (C) Systolic blood pressure of pregnant mice in control (n = 6 dam), L-NAME (n = 7 dams), and L-NAME + SRT2104 group (n = 7 dams). (D–F) Fetal weight, (E) crown-rump length,and (F) placental weight at E18.5 in different groups; n = 85 fetuses from 6 dams in the control group, n = 98 fetuses from 7 dams in the L-NAME group, and n = 81 fetuses from 7 dams in the L-NAME + SRT2104 group. (G) H&E staining of placental sections at E18.5. The LZ and JZ areas and the Lz/Jz ratio were quantified; Scale bars: 1000 μm (upper panel), 200um (lower panel); n = 3. (H) H&E staining of maternal kidney sections at E18.5, and measurement of Bowman space; Scale bars: 200 μm; n = 3. LZ, Labyrinth zone; JZ, Junction zone. One-way ANOVA and Tukey’s multiple comparison test. All data are presented as the means ± SEM.
    Srt2104 Srt, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/srt2104+srt/SRT+2104/pm40999873-397-3-9
    Average 94 stars, based on 1 article reviews
    srt2104 srt - by Bioz Stars, 2026-10
    94/100 stars
    		  Buy from Supplier
    agonist srt2104  (MedChemExpress)
    94
    MedChemExpress agonist srt2104
    Fig. 2. Screening of THSWD-containing serum and agonist <t>SRT2104</t> for optimal concentration and time of administration in cell culture (A) The optimal concentration and action time of THSWD-containing serum; (B) The optimal concentration and action time of SRT2104. (n = 3, *P < 0.05, **P < 0.01).
    Agonist Srt2104, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/srt2104+srt/SRT+2104/10__1016_slash_j__jff__2024__106574-123-16-19
    Average 94 stars, based on 1 article reviews
    agonist srt2104 - by Bioz Stars, 2026-10
    94/100 stars
    		  Buy from Supplier

    Image Search Results


    SIRT1 alleviates PE-like symptoms in the mouse model (A) Schematic illustration of the experimental design. (B) Representative images of the fetuses of the Control, L-NAME, and L-NAME + SRT2104 groups; Scale bars:1 cm. (C) Systolic blood pressure of pregnant mice in control (n = 6 dam), L-NAME (n = 7 dams), and L-NAME + SRT2104 group (n = 7 dams). (D–F) Fetal weight, (E) crown-rump length,and (F) placental weight at E18.5 in different groups; n = 85 fetuses from 6 dams in the control group, n = 98 fetuses from 7 dams in the L-NAME group, and n = 81 fetuses from 7 dams in the L-NAME + SRT2104 group. (G) H&E staining of placental sections at E18.5. The LZ and JZ areas and the Lz/Jz ratio were quantified; Scale bars: 1000 μm (upper panel), 200um (lower panel); n = 3. (H) H&E staining of maternal kidney sections at E18.5, and measurement of Bowman space; Scale bars: 200 μm; n = 3. LZ, Labyrinth zone; JZ, Junction zone. One-way ANOVA and Tukey’s multiple comparison test. All data are presented as the means ± SEM.

    Journal: Frontiers in Aging

    Article Title: The SIRT1–p53 axis drives a ferro-aging-like program and aggravates trophoblast dysfunction in preeclampsia

    doi: 10.3389/fragi.2026.1838730

    Figure Lengend Snippet: SIRT1 alleviates PE-like symptoms in the mouse model (A) Schematic illustration of the experimental design. (B) Representative images of the fetuses of the Control, L-NAME, and L-NAME + SRT2104 groups; Scale bars:1 cm. (C) Systolic blood pressure of pregnant mice in control (n = 6 dam), L-NAME (n = 7 dams), and L-NAME + SRT2104 group (n = 7 dams). (D–F) Fetal weight, (E) crown-rump length,and (F) placental weight at E18.5 in different groups; n = 85 fetuses from 6 dams in the control group, n = 98 fetuses from 7 dams in the L-NAME group, and n = 81 fetuses from 7 dams in the L-NAME + SRT2104 group. (G) H&E staining of placental sections at E18.5. The LZ and JZ areas and the Lz/Jz ratio were quantified; Scale bars: 1000 μm (upper panel), 200um (lower panel); n = 3. (H) H&E staining of maternal kidney sections at E18.5, and measurement of Bowman space; Scale bars: 200 μm; n = 3. LZ, Labyrinth zone; JZ, Junction zone. One-way ANOVA and Tukey’s multiple comparison test. All data are presented as the means ± SEM.

    Article Snippet: Mice in the L-NAME + SRT2104 group additionally received intraperitoneal SRT2104 (25 mg/kg/day; Cat. No. HY-15262; MedChemExpress, Monmouth Junction, NJ, United States), as previously described ( ).

    Techniques: Control, Staining, Comparison

    Fig. 2. Screening of THSWD-containing serum and agonist SRT2104 for optimal concentration and time of administration in cell culture (A) The optimal concentration and action time of THSWD-containing serum; (B) The optimal concentration and action time of SRT2104. (n = 3, *P < 0.05, **P < 0.01).

    Journal: Journal of Functional Foods

    Article Title: Taohong Siwu Decoction improves cerebral ischemia–reperfusion injury through SIRT1/FOXO1 signaling pathway

    doi: 10.1016/j.jff.2024.106574

    Figure Lengend Snippet: Fig. 2. Screening of THSWD-containing serum and agonist SRT2104 for optimal concentration and time of administration in cell culture (A) The optimal concentration and action time of THSWD-containing serum; (B) The optimal concentration and action time of SRT2104. (n = 3, *P < 0.05, **P < 0.01).

    Article Snippet: Real-time RT-qPCR was used to measure the mRNA expression of SIRT1 to screen the effect of agonist SRT2104 (1093403–33-8; MedChemExpress, Monmouth Junction, NJ, USA) on the proliferation of PC12 cells in the OGD/R model. Total cellular RNA was extracted using the TRIzol® kit (Thermo Scientific, Waltham, MA, USA).

    Techniques: Concentration Assay, Cell Culture

    Fig. 9. Revalidation of the effect of THSWD-regulated SIRT1/FOXO1 signaling pathway on autophagy and apoptosis in OGD/R PC12 cells (A) Immunofluorescence detects Bax, cleaved-Caspase-3, Bcl-2, P62, LC3II/I, SIRT1 and FOXO1 proteins; (B) Expression of Bax, cleaved-Caspase-3, Bcl-2, P62, LC3II/I, SIRT1 and FOXO1 proteins. (n = 3, ##P < 0.01 vsControl; **P < 0.01 vs OGD/R; ***P < 0.01 vs OGD/R + SRT2104).

    Journal: Journal of Functional Foods

    Article Title: Taohong Siwu Decoction improves cerebral ischemia–reperfusion injury through SIRT1/FOXO1 signaling pathway

    doi: 10.1016/j.jff.2024.106574

    Figure Lengend Snippet: Fig. 9. Revalidation of the effect of THSWD-regulated SIRT1/FOXO1 signaling pathway on autophagy and apoptosis in OGD/R PC12 cells (A) Immunofluorescence detects Bax, cleaved-Caspase-3, Bcl-2, P62, LC3II/I, SIRT1 and FOXO1 proteins; (B) Expression of Bax, cleaved-Caspase-3, Bcl-2, P62, LC3II/I, SIRT1 and FOXO1 proteins. (n = 3, ##P < 0.01 vsControl; **P < 0.01 vs OGD/R; ***P < 0.01 vs OGD/R + SRT2104).

    Article Snippet: Real-time RT-qPCR was used to measure the mRNA expression of SIRT1 to screen the effect of agonist SRT2104 (1093403–33-8; MedChemExpress, Monmouth Junction, NJ, USA) on the proliferation of PC12 cells in the OGD/R model. Total cellular RNA was extracted using the TRIzol® kit (Thermo Scientific, Waltham, MA, USA).

    Techniques: Immunofluorescence, Expressing